If you have not been in Panama, then I strongly advise you to visit this small and beautiful country in Central America. There are well combined styles of America and Europe. High-rise buildings in harmony with the office buildings and luxurious shopping centers, with easy to find all the delights of the European cuisine and other edible pleasures of a cozy pastry café with good coffee and food to the most refined taste, thus, like in US, lots of food, each meter can be something to eat and drink, from hamburgers and Chinese food to the Dutch pancakes and ice cream. In the capital there is a Subway (Metro), comfortable buses, so that in the transport component you will feel no worse than in Europe. Medicine is also on the level, many private hospitals and expensive equipment for surveys of any complexity, and can be at any price - from the most prestigious hospitals to the regional health centers, where also there is a quality, but a very modest money. Panama is one of the few countries where you can combine leisure and business.
If we talk about business, it is not a problem. You can do any business for a small investment and a minimum of securities and without fear from the regulatory authorities, monitoring just the minimum, you yourself will be interested to sell quality services, fighting for the clients, as Panamanians love the new and fashionable stuff. But the most profitable business here - is real estate. Buy an apartment or office -  is easy enough, but gives back quickly and for the good money, i.e. for dollars. Special demand for apartments costing up to 200 thousand dollars - and rented quickly and easily sold, of course, a lot of real estate and for large sums, but they will be difficult to find a buyer or tenant. In the country there are many foreigners from different countries, so the demand is growing and the price of rent increases. So think and invest in real estate right here and do not regret it. While in other cities, you will receive your dividends in US dollars only at the expense of here and enjoy it at any point.
Ask me and I will answer all your questions.